The -dbsize option
Sets the effective size of the database, i.e. the size assumed by the E-value calculation.
With the search command, the default size is the number of chains in the
database.
With the alignpair command, the default size is 10,000.
Example
reseek -search 1abc.pdb -db scop40.cal -dbsize 1e6 \
-fast -output hits.tsv -columns query+target+evalue