Reseek documentation

Fast, accurate protein structure search
Reseek more accurate for protein structure alignment and search than all current methods, including DALI, TM-align and Foldseek. Speed is similar to Foldseek. Reseek is the only algorithm to report robust E-values for protein structure search.

You can read the paper here: https://doi.org/10.1093/bioinformatics/btae687.

Benchmark results (Oct. 2024) Reseek

Video talks on 16S data analysis posted.

URMAP ultra-fast read mapper posted (paper).

~20% of taxonomy annotations in SILVA and Greengenes are wrong (paper).

Taxonomy prediction is <50% accurate for 16S V4 sequences (paper).

97% OTU threshold is wrong for species, should be 99% for full-length 16S, 100% V4 (paper).