Video talks on 16S data analysis posted.

URMAP ultra-fast read mapper posted (paper).

~20% of taxonomy annotations in SILVA and Greengenes are wrong (paper).

Taxonomy prediction is <50% accurate for 16S V4 sequences (paper).

97% OTU threshold is wrong for species, should be 99% for full-length 16S, 100% V4 (paper).

Denoising

See also
UNOISE algorithm
unoise3 command

Denoising, also called noise reduction, is a generic term for a process that removes noise from a signal (see Wikipedia article). In next-generation sequencing, denoising generally refers to a computational method for removing sequence errors from amplicon reads or, equivalently, identifying the correct biological sequences in the reads.