New paper shows that ~20% of taxonomy
annotations are wrong in SILVA and Greengenes.
New paper shows that taxonomy
prediction accuracy is <50% for V4 sequences.
PeerJ paper shows low
accuracy of closed- and open-ref. QIIME OTUs.
New paper shows
97% OTU threshold is too low, especially for V4.
USEARCH v10.0 posted.
UPARSE tutorial video
posted on YouTube. Make OTUs from MiSeq reads.
High-throughput search and clustering
USEARCH is a unique sequence analysis tool with
thousands of users world-wide. USEARCH offers search and clustering
algorithms that are often orders of magnitude faster than BLAST.
Improved productivity and insights
USEARCH combines many different algorithms into
a single package with outstanding documentation and support. This cuts
your learning curve, reduces the number of steps you need to take for
a given task, and slashes compute times. USEARCH will encourage you to
explore your data, enabling new insights and suggesting new analyses
that you might not have tried with slower tools.
Free for most users
Licenses to use 32-bit USEARCH are offered at
no charge for all users, including commercial.
You can download the
32-bit version here.