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USEARCH algorithms
 
See also
  USEARCH commands
  Search flowchart
 
Algorithm   Description
USEARCH   Ultra-fast search for high-identity top hit or hits.
UCLUST   Ultra-fast general-purpose clustering. See also OTU clustering.
UBLAST   Fast, sensitive database search.
UPARSE-REF   Error inference by maximum parsimony. Used for annotating sequences obtained in mock community experiments.
UPARSE-OTU   Greedy construction of OTUs. Used for OTU clustering of marker gene reads (obtained from mock or real environmental samples).
UCHIME   Search for chimeric sequences.
Dereplication   Removal of duplicated sequences.
ORF detection   Identification of Open Reading Frames (ORFs) in nucleotide sequences.
Local clustering   Clustering using local alignments
Masking   Detection of repetitive or low-complexity regions.
Read quality filtering   Quality filtering of reads in FASTQ format.