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Fast, accurate read mapping with highly compressed output
The Ultra-fast Read Mapper (URMAP) is ~10x faster than BWA and Bowtie with comparable accuracy on benchmark tests.

URMAP offers faster options when when very high accuracy is not essential, e.g. for nucleosome position inference in cfDNA reads. In such applications, speeds ~20x faster than BWA can be achieved (up to ~1M reads per second on a 24-core server).

URMAP supports SAM and also SUM, which is ~30x smaller than SAM. SUM can be converted to SAM, enabling efficient archiving of large datasets.

Paper here: https://www.biorxiv.org/content/10.1101/2020.01.12.903351v1.